TDP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all TDP1 蛋白
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TDP1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human TDP1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TDP1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 别名
- Tdp1 (TDP1 产品)
- 别名
- 2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
- 背景
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).
- 分子量
- 68.2 kDa
- NCBI登录号
- NP_001008744
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