TDP1 蛋白
(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TDP1 Protein (AA 1-608) (GST tag) | 人 | 小麦胚 |
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| TDP1 Protein (AA 1-608) (His tag) | 人 | Baculovirus infected Insect Cells |
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| TDP1 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| TDP1 Protein (AA 1-609) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| TDP1 Protein (AA 1-608) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| TDP1 Protein (AA 4-215) (His tag,GST tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TDP1 Protein (AA 1-271) (His tag,GST tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| TDP1 Protein (AA 1-151) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TDP1 Protein (His tag,GST tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| TDP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| TDP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| TDP1 Protein (AA 1-609) (His tag) | 大鼠 | 酵母菌 |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our TDP1 蛋白
: "Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends." in: Nucleic acids research, Vol. 35, Issue 11, pp. 3797-809, (2007) (PubMed).
Aliases for TDP1 蛋白
tyrosyl-DNA phosphodiesterase 1 (TDP1) 蛋白tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10) 蛋白
tyrosyl-DNA phosphodiesterase 1 (Tdp1) 蛋白
tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L) 蛋白
tyrosyl-DNA phosphodiesterase 1 (tdp1) 蛋白
tyrosyl-DNA phosphodiesterase-like protein (TDP1) 蛋白
tyrosyl-DNA phosphodiesterase 1 (PTRG_11198) 蛋白
tyrosyl-DNA phosphodiesterase 1 (MCYG_02121) 蛋白
tyrosyl-DNA phosphodiesterase 1 (MGYG_03035) 蛋白
2810481F14Rik 蛋白
4921509N21Rik 蛋白
AI838772 蛋白
AW493413 蛋白
E430034L06Rik 蛋白
F8M21.60 蛋白
F8M21_60 蛋白
MGC83708 蛋白
MLZ-501 蛋白
SCAN1 蛋白
tdp1 蛋白
TDP1 蛋白
tyrosyl-DNA phosphodiesterase 1 蛋白
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