TDG 蛋白
(Thymine-DNA Glycosylase (TDG))
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008].
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custom-made
TDG
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
TDG
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aliases for TDG 蛋白
thymine DNA glycosylase (TDG) 蛋白thymine DNA glycosylase, tandem duplicate 1 (tdg.1) 蛋白
putative g/t mismatch-specific thymine DNA glycosylase (Smp_149220) 蛋白
G/T mismatch-specific thymine DNA glycosylase (Tsp_05734) 蛋白
thymine DNA glycosylase S homeolog (tdg.S) 蛋白
thymine DNA glycosylase (tdg) 蛋白
thymine DNA glycosylase (Tdg) 蛋白
thymine-DNA glycosylase (Tdg) 蛋白
5-MCDG 蛋白
E130317C12Rik 蛋白
hTDG 蛋白
JZA-3 蛋白
Jza1 蛋白
MGC82456 蛋白
MGC89441 蛋白
wu:fb44b11 蛋白
zgc:110622 蛋白
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