Epigen Protein (AA 23-110) (His tag)
-
- 抗原 See all Epigen (EPGN) 蛋白
- Epigen (EPGN) (Epithelial Mitogen (EPGN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-110
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This Epigen protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE KHHHHHH
- 纯度
- > 90 % by SDS - PAGE
- 内毒素水平
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product EPGN 蛋白
-
Epithelial Mitogen (EPGN) (AA 24-95) protein (His tag)
EPGN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Epithelial Mitogen (EPGN) (AA 1-133) protein (GST tag)EPGN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Epithelial Mitogen (EPGN) (AA 23-154) protein (rho-1D4 tag)Crystallography grade EPGN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epithelial Mitogen (EPGN) (AA 19-152) protein (rho-1D4 tag)Crystallography grade EPGN 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- Epigen (EPGN) (Epithelial Mitogen (EPGN))
- 别名
- EPGN (EPGN 产品)
- 别名
- ALGV3072 Protein, EPG Protein, PRO9904 Protein, 2310069M11Rik Protein, epigen Protein, RGD1560084 Protein, epithelial mitogen Protein, EPGN Protein, Epgn Protein
- 背景
- EPGN, also known as epigen isoform 1, is a novel member of the epidermal growth factor superfamily. It is the last ligand of ErbB receptors and reveals intricate relationships between affinity and mitogenicity. It stimulated the proliferation of HaCaT cells, and this proliferation was blocked by an antibody to the extracellular domain of the receptor tyrosine kinase c-erbB-1. It also may constitute a novel molecular target for wound-healing therapy with its ability to promote the growth of epithelial cells. It has been reported to have high mitogenic activity but low affinity for its receptor. It has been reported in cancer specimens of the breast, bladder, and prostate. Recombinant human EPGN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 10.8kDa (97aa) 13.5-18kDa (SDS-PAGE under reducing conditions)
- NCBI登录号
- NP_001257918
- UniProt
- Q6UW88
- 途径
- RTK signaling, EGFR Signaling Pathway
-
