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LAMP2 Protein (AA 29-375) (His tag)
LAMP2
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
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LAMP2
(Lysosomal-Associated Membrane Protein 2 (LAMP2))
蛋白类型
Recombinant
产品特性
AA 29-375
宿主
All origins for LAMP2 蛋白
人
资源
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Baculovirus infected Insect Cells
标记
This LAMP2 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
序列
ADPLELNLTD SENATCLYAK WQMNFTVRYE TTNKTYKTVT ISDHGTVTYN GSICGDDQNG PKIAVQFGPG FSWIANFTKA ASTYSIDSVS FSYNTGDNTT FPDAEDKGIL TVDELLAIRI PLNDLFRCNS LSTLEKNDVV QHYWDVLVQA FVQNGTVSTN EFLCDKDKTS TVAPTIHTTV PSPTTTPTPK EKPEAGTYSV NNGNDTCLLA TMGLQLNITQ DKVASVININ PNTTHSTGSC RSHTALLRLN SSTIKYLDFV FAVKNENRFY LKEVNISMYL VNGSVFSIAN NNLSYWDAPL GSSYMCNKEQ TVSVSGAFQI NTFDLRVQPF NVTQGKYSTA QDCSADDDNF HHHHHH
纯度
> 90 % by SDS - PAGE
内毒素水平
< 1.0 EU per 1ug of protein (determined by LAL method)
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
LAMP2
(Lysosomal-Associated Membrane Protein 2 (LAMP2))
别名
LAMP2 (LAMP2 产品 )
别名
CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein
背景
LAMP2, also known as lysosome-associated membrane glycoprotein 2 isoform A, is a major component of lysosomal membranes. It provides selectins with carbohydrate ligands. This protein mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. Deficiency of LAMP2 is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. Recombinant human LAMP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
39.4kDa (356aa) 57-70KDa (SDS-PAGE under reducing conditions.)
NCBI登录号
NP_002285
UniProt
P13473
途径
Autophagy
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LAMP2 蛋白
LAMP2 Protein (AA 29-375) (His tag) (ABIN5855013)