LAMP2 Protein (His tag)
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- 抗原 See all LAMP2 蛋白
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This LAMP2 protein is labelled with His tag.
- 原理
- Recombinant Human LAMP2/CD107b Protein (His Tag)(Active)
- 序列
- Leu29-Ile375
- 产品特性
- Recombinant Human Lysosome-Associated Membrane Glycoprotein 2 is produced by our Mammalian expression system and the target gene encoding Leu29-Ile375 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LGALS3(Cat: PKSH032474) at 1.5μg/ml(100 μl/well) can bind Human LAMP2-His. The ED50 of Human LAMP2-His is 12.73 ug/ml .
- Top Product
- Discover our top product LAMP2 蛋白
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Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) protein (GST tag)
LAMP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 34-231) protein (His-IF2DI Tag)LAMP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lysosomal-Associated Membrane Protein 2 (LAMP2) protein (His tag)LAMP2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-375) protein (His tag)Crystallography grade LAMP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 26-379) protein (His tag)Crystallography grade LAMP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-410) protein (rho-1D4 tag)Crystallography grade LAMP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 26-415) protein (rho-1D4 tag)Crystallography grade LAMP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- 别名
- LAMP2/CD107b (LAMP2 产品)
- 别名
- CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein
- 背景
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Background: Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110 kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.
Synonym: Lysosome-Associated Membrane Glycoprotein 2, LAMP-2, Lysosome-Associated Membrane Protein 2, CD107 Antigen-Like Family Member B, CD107b, LAMP2
- 分子量
- 33.9 kDa
- UniProt
- P13473
- 途径
- Autophagy
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