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Integrin beta 2 Protein (ITGB2) (AA 23-700) (His tag)

ITGB2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN5854581
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 蛋白
    Integrin beta 2 (ITGB2)
    蛋白类型
    Recombinant
    产品特性
    AA 23-700
    宿主
    • 9
    • 4
    • 2
    资源
    • 7
    • 4
    • 3
    • 1
    Baculovirus infected Insect Cells
    标记
    This Integrin beta 2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    QECTKFKVSS CRECIESGPG CTWCQKLNFT GPGDPDSIRC DTRPQLLMRG CAADDIMDPT SLAETQEDHN GGQKQLSPQK VTLYLRPGQA AAFNVTFRRA KGYPIDLYYL MDLSYSMLDD LRNVKKLGGD LLRALNEITE SGRIGFGSFV DKTVLPFVNT HPDKLRNPCP NKEKECQPPF AFRHVLKLTN NSNQFQTEVG KQLISGNLDA PEGGLDAMMQ VAACPEEIGW RNVTRLLVFA TDDGFHFAGD GKLGAILTPN DGRCHLEDNL YKRSNEFDYP SVGQLAHKLA ENNIQPIFAV TSRMVKTYEK LTEIIPKSAV GELSEDSSNV VQLIKNAYNK LSSRVFLDHN ALPDTLKVTY DSFCSNGVTH RNQPRGDCDG VQINVPITFQ VKVTATECIQ EQSFVIRALG FTDIVTVQVL PQCECRCRDQ SRDRSLCHGK GFLECGICRC DTGYIGKNCE CQTQGRSSQE LEGSCRKDNN SIICSGLGDC VCGQCLCHTS DVPGKLIYGQ YCECDTINCE RYNGQVCGGP GRGLCFCGKC RCHPGFEGSA CQCERTTEGC LNPRRVECSG RGRCRCNVCE CHSGYQLPLC QECPGCPSPC GKYISCAECL KFEKGPFGKN CSAACPGLQL SNNPVKGRTC KERDSEGCWV AYTLEQQDGM DRYLIYVDES RECVAGPNLE HHHHHH
    纯度
    > 85 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product ITGB2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    ITGB2 (ITGB2 产品)
    别名
    CD18 Protein, LAD Protein, LCAMB Protein, LFA-1 Protein, MAC-1 Protein, MF17 Protein, MFI7 Protein, 2E6 Protein, AI528527 Protein, Cd18 Protein, Lfa1 Protein, ITGB2 Protein, itgb2 Protein, itgb2-a Protein, itgb2-b Protein, integrin subunit beta 2 Protein, integrin beta 2 Protein, integrin subunit beta 2 S homeolog Protein, ITGB2 Protein, Itgb2 Protein, itgb2.S Protein
    背景
    ITGB2, also known as integrin beta-2, is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It may belong to an extended family of cell surface molecules including the fibronectin binding protein. Also It is a complement receptor type 3 (CR3). It triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Recombinant human ITGB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    75.9kDa (686aa) 70-100kDa (SDS-PAGE under reducing conditions)
    NCBI登录号
    NP_000202
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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