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Integrin beta 2 Protein (ITGB2) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ITGB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713476
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 蛋白
    Integrin beta 2 (ITGB2)
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 9
    • 4
    • 2
    资源
    • 7
    • 5
    • 3
    HEK-293 Cells
    标记
    This Integrin beta 2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CD18 / ITGB2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ITGB2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • De Franceschi, Peuhu, Parsons, Rissanen, Vattulainen, Salmi, Ivaska, Pouwels: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).

  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    Cd18,itgb2 (ITGB2 产品)
    别名
    CD18 Protein, LAD Protein, LCAMB Protein, LFA-1 Protein, MAC-1 Protein, MF17 Protein, MFI7 Protein, 2E6 Protein, AI528527 Protein, Cd18 Protein, Lfa1 Protein, ITGB2 Protein, itgb2 Protein, itgb2-a Protein, itgb2-b Protein, integrin subunit beta 2 Protein, integrin beta 2 Protein, integrin subunit beta 2 S homeolog Protein, ITGB2 Protein, Itgb2 Protein, itgb2.S Protein
    背景
    This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
    分子量
    82.5 kDa
    NCBI登录号
    NP_001120963
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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