IL-10RA Protein (AA 22-235) (His tag)
IL10RA
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 85 % by SDS - PAGE.
SDS
1 image
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- 抗原 See all IL-10RA (IL10RA) 蛋白
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-235
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This IL-10RA protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- HGTELPSPPS VWFEAEFFHH ILHWTPIPNQ SESTCYEVAL LRYGIESWNS ISNCSQTLSY DLTAVTLDLY HSNGYRARVR AVDGSRHSNW TVTNTRFSVD EVTLTVGSVN LEIHNGFILG KIQLPRPKMA PANDTYESIF SHFREYEIAI RKVPGNFTFT HKKVKHENFS LLTSGEVGEF CVQVKPSVAS RSNKGMWSKE ECISLTRQYF TVTNHHHHHH
- 纯度
- > 85 % by SDS - PAGE.
- 内毒素水平
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product IL10RA 蛋白
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Interleukin 10 Receptor, alpha (IL10RA) (AA 22-235) protein (His-Avi Tag)
IL10RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 Receptor, alpha (IL10RA) (AA 22-233) protein (His tag)IL10RA 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- Liquid. In phosphate buffered saline ( pH 7.4) containing 10 % glycerol.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- 别名
- IL10RA (IL10RA 产品)
- 别名
- IL10R1 Protein, IL10RA Protein, CD210 Protein, CD210a Protein, CDW210A Protein, HIL-10R Protein, IL-10R1 Protein, IL10R Protein, AW553859 Protein, CDw210 Protein, CDw210a Protein, Il10r Protein, mIL-10R Protein, interleukin 10 receptor subunit alpha Protein, interleukin 10 receptor, alpha Protein, IL10RA Protein, Il10ra Protein
- 背景
- IL10RA, also known as Interleukin-10 receptor subunit alpha, is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. It has been shown to interact with Interleukin 10 and Janus kinase 1. Recombinant human IL10RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 25.2kDa (220aa) 228-40kDa (SDS-PAGE under reducing conditions.)
- NCBI登录号
- NP_001549
- UniProt
- Q13651
- 途径
- Growth Factor Binding
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