SMARCA4 Protein (AA 362-549) (His tag)
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- 抗原 See all SMARCA4 蛋白
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 362-549
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This SMARCA4 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSDPVEILQ EREYRLQARI AHRIQELENL PGSLAGDLRT KATIELKALR LLNFQRQLRQ EVVVCMRRDT ALETALNAKA YKRSKRQSLR EARITEKLEK QQKIEQERKR RQKHQEYLNS ILQHAKDFKE YHRSVTGKIQ KLTKAVATYH ANTEREQKKE NERIEKERMR RLMAEDEEGY RKLIDQKKDK R
- 纯度
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product SMARCA4 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
- 别名
- SMARCA4 (SMARCA4 产品)
- 别名
- SMARCA4 Protein, BAF190 Protein, BAF190A Protein, BRG1 Protein, MRD16 Protein, RTPS2 Protein, SNF2 Protein, SNF2L4 Protein, SNF2LB Protein, SWI2 Protein, hSNF2b Protein, brg-1 Protein, Brg1 Protein, HP1-BP72 Protein, SNF2beta Protein, SW1/SNF Protein, b2b692Clo Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Protein, SMARCA4 Protein, Smarca4 Protein
- 背景
- SMARCA4 is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.. Recombinant human SMARCA4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 25.0kDa (211aa)
- NCBI登录号
- NP_001122321
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
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