Parkin Protein (AA 1-465) (His tag)
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- 抗原 See all Parkin (PARK2) 蛋白
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-465
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Parkin protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MIVFVRFNSS HGFPVEVDSD TSIFQLKEVV AKRQGVPADQ LRVIFAGKEL RNDWTVQNCD LDQQSIVHIV QRPWRKGQEM NATGGDDPRN AAGGCEREPQ SLTRVDLSSS VLPGDSVGLA VILHTDSRKD SPPAGSPAGR SIYNSFYVYC KGPCQRVQPG KLRVQCSTCR QATLTLTQGP SCWDDVLIPN RMSGECQSPH CPGTSAEFFF KCGAHPTSDK ETSVALHLIA TNSRNITCIT CTDVRSPVLV FQCNSRHVIC LDCFHLYCVT RLNDRQFVHD PQLGYSLPCV AGCPNSLIKE LHHFRILGEE QYNRYQQYGA EECVLQMGGV LCPRPGCGAG LLPEPDQRKV TCEGGNGLGC GFAFCRECKE AYHEGECSAV FEASGTTTQA YRVDERAAEQ ARWEAASKET IKKTTKPCPR CHVPVEKNGG CMHMKCPQPQ CRLEWCWNCG CEWNRVCMGD HWFDV
- 纯度
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product PARK2 蛋白
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Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-165) protein (His-IF2DI Tag)
PARK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-387) protein (GST tag)PARK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 288-387) protein (GST tag)PARK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-465) protein (Strep Tag)Crystallography grade PARK2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-464) protein (Strep Tag)Crystallography grade PARK2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-465), (full length) protein (His-SUMO Tag)PARK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- 别名
- PARK2 (PARK2 产品)
- 别名
- CG10523 Protein, Dmel\\CG10523 Protein, Dpark Protein, SD01679 Protein, dpk Protein, AR-JP Protein, LPRS2 Protein, PDJ Protein, PRKN Protein, Park Protein, Prkn Protein, si:ch211-123f21.1 Protein, zgc:112390 Protein, pdr-1 Protein, PARK2 Protein, parkin Protein, parkin RBR E3 ubiquitin protein ligase Protein, Parkinson disease (autosomal recessive, juvenile) 2, parkin Protein, park Protein, PRKN Protein, Prkn Protein, prkn Protein, CpipJ_CPIJ014867 Protein, Park2 Protein
- 背景
- The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. Recombinant human PARK2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 53.8 kDa (485aa)
- NCBI登录号
- NP_004553
- UniProt
- O60260
- 途径
- Autophagy, Ubiquitin Proteasome Pathway
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