CCM2 Protein (AA 66-353) (His tag)
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- 抗原 See all CCM2 蛋白
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 66-353
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CCM2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSEVKYLGQ LTSIPGYLNP SSRTEILHFI DNAKRAHQLP GHLTQEHDAV LSLSAYNVKL AWRDGEDIIL RVPIHDIAAV SYVRDDAAHL VVLKTDDSST KVDIKETYEV EASTFCFPES VDVGGASPHS KTISESELSA SATELLQDYM LTLRTKLSSQ EIQQFAALLH EYRNGASIHE FCINLRQLYG DSRKFLLLGL RPFIPEKDSQ HFENFLETIG VKDGRGIITD SFGRHRRALS TTSSSTTNGN RATGSSDDRS APSEGDEWDR MISDISSDIE ALGCSMDQDS A
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CCM2 蛋白
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Cerebral Cavernous Malformation 2 (CCM2) (AA 66-353) protein (His tag)
CCM2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) protein (GST tag)CCM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) protein (GST tag)CCM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cerebral Cavernous Malformation 2 (CCM2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CCM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- 别名
- CCM2 (CCM2 产品)
- 别名
- C7orf22 Protein, OSM Protein, malcavernin Protein, CCM2 Protein, BC029157 Protein, TUF2 Protein, vtn Protein, zgc:110233 Protein, CCM2 scaffolding protein Protein, cerebral cavernous malformation 2 Protein, malcavernin Protein, CCM2 Protein, Ccm2 Protein, LOC100304744 Protein, ccm2 Protein
- 背景
- CCM2 provides instructions for making a protein called malcavernin, which strengthens the interactions between cells that form blood vessels and limits leakage from the vessels. It interacts with a number of other proteins to form a complex that is found in the junctions that connect neighboring cells. It helps turn off (suppress) a signaling molecule known as RhoA-GTPase. Recombinant human CCM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- 分子量
- 34.3kDa (311aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_001161407
- UniProt
- Q9BSQ5
- 途径
- Cell-Cell Junction Organization
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