CCM2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all CCM2 蛋白
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CCM2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Malcavernin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CCM2 蛋白
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Cerebral Cavernous Malformation 2 (CCM2) (AA 66-353) protein (His tag)
CCM2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) protein (GST tag)CCM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) protein (GST tag)CCM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) protein (Strep Tag)Crystallography grade CCM2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Cerebral Cavernous Malformation 2 (CCM2) (AA 1-453) protein (Strep Tag)Crystallography grade CCM2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- 别名
- Malcavernin (CCM2 产品)
- 别名
- C7orf22 Protein, OSM Protein, malcavernin Protein, CCM2 Protein, BC029157 Protein, TUF2 Protein, vtn Protein, zgc:110233 Protein, CCM2 scaffolding protein Protein, cerebral cavernous malformation 2 Protein, malcavernin Protein, CCM2 Protein, Ccm2 Protein, LOC100304744 Protein, ccm2 Protein
- 背景
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009].
- 分子量
- 48.7 kDa
- NCBI登录号
- NP_113631
- 途径
- Cell-Cell Junction Organization
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