CCM2 蛋白
(Cerebral Cavernous Malformation 2 (CCM2))
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CCM2 Protein (AA 66-353) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CCM2 Protein (AA 66-353) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| CCM2 Protein (AA 1-444) (GST tag) | 人 | 小麦胚 |
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| CCM2 Protein (AA 1-444) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| CCM2 Protein (AA 1-453) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| CCM2 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CCM2 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| CCM2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Aliases for CCM2 蛋白
CCM2 scaffolding protein (CCM2) 蛋白CCM2 scaffolding protein (Ccm2) 蛋白
cerebral cavernous malformation 2 (Ccm2) 蛋白
malcavernin (LOC100304744) 蛋白
cerebral cavernous malformation 2 (ccm2) 蛋白
BC029157 蛋白
C7orf22 蛋白
CCM2 蛋白
malcavernin 蛋白
OSM 蛋白
TUF2 蛋白
vtn 蛋白
zgc:110233 蛋白
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