CCL2 蛋白
(Chemokine (C-C Motif) Ligand 2 (CCL2))
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CCL2 Protein (AA 24-99) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| CCL2 Protein (AA 24-99) (Biotin) | 人 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-99) (His-Avi Tag) | 人 | HEK-293 Cells |
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| CCL2 Protein (AA 24-99) (His tag) | Cynomolgus | HEK-293 Cells |
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| CCL2 Protein (AA 24-99) | 人 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-148) (His-IF2DI Tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-96) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-148) (His-IF2DI Tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-99) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 1-99) (GST tag) | 人 | 小麦胚 |
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| CCL2 Protein (AA 24-148) (His tag) | 小鼠 | HEK-293 Cells |
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| CCL2 Protein (AA 24-148) (His tag) | 大鼠 | Mammalian Cells |
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| CCL2 Protein (AA 24-96) | 小鼠 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-148) (His tag) | 大鼠 | 人细胞 |
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| CCL2 Protein (His tag) | 人 | HEK-293 Cells |
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| CCL2 蛋白 | 小鼠 | Yeast (Pichia pastoris) |
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| CCL2 Protein (AA 24-96) | 小鼠 | HEK-293T Cells |
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| CCL2 Protein (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| CCL2 Protein (AA 24-125) (His-IF2DI Tag) | 兔 | 大肠杆菌（E. Coli） |
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| CCL2 Protein (AA 24-99) (His-IF2DI Tag) | Pig | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- FACS (Flow Cytometry: 有验证图片)
- CA (Cellular Assay: 有验证图片)
- CMA (Cell Migration Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS PAGE
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- CA (Cellular Assay: 有验证图片)
- CMA (Cell Migration Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 % by SDS PAGE
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 大鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 92 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293T Cells
- 蛋白类型
- Recombinant
- 纯度
- > 98 % as analyzed by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 兔
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 85 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- Pig
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Latest Publications for our CCL2 蛋白
: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis." in: Circulation, Vol. 127, Issue 18, pp. 1888-902, (2013) (PubMed).
: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
: "Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 8, pp. 1746-52, (2006) (PubMed).
: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
: "Leukocyte migration and activation by murine chemokines." in: Immunobiology, Vol. 195, Issue 4-5, pp. 499-521, (1997) (PubMed).
: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, (1997) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 7, pp. 3541-9, (1994) (PubMed).
: "Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 8, pp. 3708-16, (1994) (PubMed).
: "NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis." in: Circulation, Vol. 127, Issue 18, pp. 1888-902, (2013) (PubMed).
: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).
: "Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 8, pp. 1746-52, (2006) (PubMed).
: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).
: "Leukocyte migration and activation by murine chemokines." in: Immunobiology, Vol. 195, Issue 4-5, pp. 499-521, (1997) (PubMed).
: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, (1997) (PubMed).
: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).
: "Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 7, pp. 3541-9, (1994) (PubMed).
: "Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 8, pp. 3708-16, (1994) (PubMed).
Aliases for CCL2 蛋白
C-C motif chemokine ligand 2 (CCL2) 蛋白chemokine (C-C motif) ligand 2 (Ccl2) 蛋白
C-C motif chemokine ligand 2 (Ccl2) 蛋白
chemokine (C-C motif) ligand 2 (CCL2) 蛋白
C-C motif chemokine 2 (LOC101120093) 蛋白
AI323594 蛋白
GDCF-2 蛋白
HC11 蛋白
HSMCR30 蛋白
JE 蛋白
MCAF 蛋白
MCP-1 蛋白
MCP-1A 蛋白
MCP1 蛋白
MCP1A 蛋白
SCYA2 蛋白
Scya2 蛋白
Sigje 蛋白
SMC-CF 蛋白
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