Renin Protein (REN) (AA 67-406) (His tag)
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- 抗原 See all Renin (REN) 蛋白
- Renin (REN)
- 蛋白类型
- Recombinant
- 产品特性
- AA 67-406
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Renin protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSHMLTLGN TTSSVILTNY MDTQYYGEIG IGTPPQTFKV VFDTGSSNVW VPSSKCSRLY TACVYHKLFD ASDSSSYKHN GTELTLRYST GTVSGFLSQD IITVGGITVT QMFGEVTEMP ALPFMLAEFD GVVGMGFIEQ AIGRVTPIFD NIISQGVLKE DVFSFYYNRD SENSQSLGGQ IVLGGSDPQH YEGNFHYINL IKTGVWQIQM KGVSVGSSTL LCEDGCLALV DTGASYISGS TSSIEKLMEA LGAKKRLFDY VVKCNEGPTL PDISFHLGGK EYTLTSADYV FQESYSSKKL CTLAIHAMDI PPPTGPTWAL GATFIRKFYT EFDRRNNRIG FALAR
- 纯度
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product REN 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- Renin (REN)
- 别名
- REN (REN 产品)
- 别名
- HNFJ2 Protein, RATRENAA Protein, RENAA Protein, Ren1 Protein, D19352 Protein, Ren Protein, Ren-1 Protein, Ren-A Protein, Ren1c Protein, Ren1d Protein, Rn-1 Protein, Rnr Protein, renin Protein, renin 1 structural Protein, REN Protein, Ren Protein, Ren1 Protein, ren Protein
- 背景
- Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. Recombinant human REN protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 39.9kDa (365aa)
- NCBI登录号
- NP_000528
- UniProt
- P00797
- 途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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