SOCS3 Protein (AA 1-225, full length) (His tag)
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- 抗原 See all SOCS3 蛋白
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-225
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宿主
- 大鼠
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资源
- 酵母菌
- 标记
- This SOCS3 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL SAEPAGTFLI RDSSDQRHFF TLSVETQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV LKLVHHYMPP PGAPSFSLPP TEPSFEVQEQ PPAQALPGGT PKRAYYIYSG GEKIPLVLSR PLSSNVATLQ HLCRKTVNGH LDSYEKVTQL PGPIREFLDQ YDAPL
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SOCS3 蛋白
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Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) protein (GST tag)
SOCS3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) protein (His-IF2DI Tag)SOCS3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) (Active) protein (His tag)SOCS3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225), (full length) protein (His-SUMO Tag)SOCS3 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- 别名
- SOCS3 (SOCS3 产品)
- 别名
- socs3 Protein, fj09e12 Protein, zgc:56537 Protein, wu:fj09e12 Protein, MGC64393 Protein, MGC75749 Protein, xsocs3 Protein, MGC81248 Protein, atod4 Protein, cis3 Protein, cish3 Protein, socs-3 Protein, ssi-3 Protein, ssi3 Protein, SOCS3 Protein, ATOD4 Protein, CIS3 Protein, Cish3 Protein, SOCS-3 Protein, SSI-3 Protein, SSI3 Protein, Cis3 Protein, EF-10 Protein, Ef10 Protein, Ssi3 Protein, Socs-3 Protein, Ssi-3 Protein, suppressor of cytokine signaling 3a Protein, suppressor of cytokine signaling 3 S homeolog Protein, suppressor of cytokine signaling 3 Protein, suppressor of cytokine signaling 3 L homeolog Protein, socs3a Protein, socs3.S Protein, socs3 Protein, socs3.L Protein, SOCS3 Protein, Socs3 Protein
- 背景
- SOCS family proteins form part of a classical negative feedback syst that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Ses to recognize IL6ST .
- 分子量
- 26.81 kDa
- UniProt
- O88583
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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