BRMS1 Protein (AA 1-235, partial) (GST tag)
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- 抗原 See all BRMS1 蛋白
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-235, partial
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This BRMS1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAA
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product BRMS1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- 别名
- BRMS1 (BRMS1 产品)
- 别名
- MGC98869 Protein, BRMS1 Protein, BRMS1L Protein, AV003220 Protein, AW554636 Protein, si:zc188c22.3 Protein, si:zc194c5.2 Protein, wu:fb57b08 Protein, zgc:56414 Protein, breast cancer metastasis suppressor 1 Protein, breast cancer metastasis-suppressor 1 Protein, breast cancer metastasis suppressor 1 L homeolog Protein, BRMS1 Protein, Brms1 Protein, brms1.L Protein, brms1 Protein
- 背景
- Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
- 分子量
- 54.7 kDa
- UniProt
- Q9HCU9
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