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BRMS1 产品

(Breast Cancer Metastasis Suppressor 1 (BRMS1))

Categories

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured BRMS1 Categories

BRMS1 抗体

High quality antibodies with extensive validation data.

BRMS1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

BRMS1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BRMS1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (8)
  • (5)
Cat. No. ABIN565191
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
Cat. No. ABIN7258182
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7265929
Quantity 100 μL
Datasheet Datasheet

Recommended BRMS1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1124133
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6202158
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6202159
Quantity 96 tests
Datasheet Datasheet

Recommended BRMS1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346875
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3090160
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3128096
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our BRMS1 Products

Ventura, Quezada, Maloney, Fernandes, Antecka, Martins, Bakalian, di Cesare, Burnier: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." in: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).

Liu, Mayo, Nagji, Hall, Shock, Xiao, Stelow, Jones: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." in: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).

Cui, Liu, He, Li, Huang, Sun, Tang, Chen, Jiang, Chen, Yun, Zeng, Guo, Wang, Ma: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." in: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).

Kim, Nam, Pyo, Jang, Kim, Kim, Boo, Lee, Yoon, Baek, Kim: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." in: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).

Nagji, Liu, Stelow, Stukenborg, Jones: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." in: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).

Wu, McEwen, Harihar, Baker, DeWald, Zhou: "BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study." in: Cancer letters, Vol. 293, Issue 1, pp. 82-91, (2010) (PubMed).

Smith, Liu, Siefert, Moskaluk, Petroni, Jones: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." in: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).

Vaidya, Sanchez, Kim, Welch: "Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells." in: Cancer letters, Vol. 281, Issue 1, pp. 100-7, (2009) (PubMed).

Frolova, Edmonds, Bodenstine, Seitz, Johnson, Feng, Welch, Frost: "A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers." in: Tumour biology, Vol. 30, Issue 3, pp. 148-59, (2009) (PubMed).

Cicek, Fukuyama, Cicek, Sizemore, Welch, Sizemore, Casey: "BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter." in: Clinical & experimental metastasis, Vol. 26, Issue 3, pp. 229-37, (2009) (PubMed).

Synonyms and alternative names related to BRMS1

breast cancer metastasis suppressor 1 (BRMS1), breast cancer metastasis-suppressor 1 (Brms1), breast cancer metastasis suppressor 1 L homeolog (brms1.L), breast cancer metastasis suppressor 1 (Brms1), breast cancer metastasis suppressor 1 (brms1), AV003220, AW554636, BRMS1, BRMS1L, MGC98869, si:zc188c22.3, si:zc194c5.2, wu:fb57b08, zgc:56414

Protein level used designations for BRMS1

  • breast cancer metastasis-suppressor 1
  • breast cancer metastasis suppressor 1
  • breast cancer metastasis-suppressor 1 homolog
  • breast cancer metastasis-suppressor 1-like protein
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