BRD4 产品
(Bromodomain Containing 4 (BRD4))
Categories
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Featured BRD4 Categories
BRD4 抗体
High quality antibodies with extensive validation data.
BRD4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BRD4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BRD4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7010051
Quantity
60 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6260309
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7127371
Quantity
100 μL
Datasheet
Datasheet
Recommended BRD4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965241
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954198
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1124204
Quantity
96 tests
Datasheet
Datasheet
Recommended BRD4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122050
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3090073
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BRD4 Products
: "BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver." in: Metabolism: clinical and experimental, Vol. 65, Issue 10, pp. 1478-88, (2017) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." in: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." in: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).
: "The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains." in: Genes & development, Vol. 29, Issue 14, pp. 1507-23, (2015) (PubMed).
: "The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors." in: PLoS ONE, Vol. 8, Issue 6, pp. e64880, (2013) (PubMed).
: "The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3." in: Molecular and cellular biology, Vol. 31, Issue 13, pp. 2641-52, (2011) (PubMed).
: "RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia." in: Nature, Vol. 478, Issue 7370, pp. 524-8, (2011) (PubMed).
: "Targeting MYC dependence in cancer by inhibiting BET bromodomains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 40, pp. 16669-74, (2011) (PubMed).
: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." in: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).
: "Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4." in: Journal of virology, Vol. 83, Issue 9, pp. 4127-39, (2009) (PubMed).
Synonyms and alternative names related to BRD4
bromodomain containing 4 L homeolog (brd4.L), bromodomain containing 4 (BRD4), bromodomain containing 4 (brd4), bromodomain-containing protein 4 (LOC100409351), bromodomain containing 4 (Brd4), BRD4, brd4-b, Brd5, CAP, fb18g03, HUNK1, HUNKI, MCAP, WI-11513, wu:fb18g03Protein level used designations for BRD4
- Bromodomain-containing protein 4B
- bromodomain-containing protein 4B
- bromodomain containing 4
- bromodomain-containing protein 4
- bromodomain 4
- bromodomain-containing protein 4-like
- bromodomain containing protein 4
- bromodomain-containing 4
- chromosome-associated protein
- bromodomain-containing 5
- fsh-like protein
- mitotic chromosome-associated protein
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