BRD2 产品
(Bromodomain Containing 2 (BRD2))
Categories
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010].
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Featured BRD2 Categories
Recommended BRD2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
Cat. No.
ABIN5542291
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN562664
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7265939
Quantity
100 μL
Datasheet
Datasheet
Recommended BRD2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN428131
Quantity
96 tests
Datasheet
Datasheet
Recommended BRD2 蛋白
Product
Reactivity
Source
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Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122047
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346854
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122048
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our BRD2 Products
: "miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons." in: Development (Cambridge, England), Vol. 145, Issue 1, (2018) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." in: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer." in: Nature, Vol. 510, Issue 7504, pp. 278-82, (2014) (PubMed).
: "Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma." in: Cancer cell, Vol. 24, Issue 5, pp. 603-16, (2013) (PubMed).
: "BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy." in: American journal of human genetics, Vol. 73, Issue 2, pp. 261-70, (2003) (PubMed).
: "Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 8, pp. 1727-37, (2002) (PubMed).
: "RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 11, Issue 8, pp. 417-24, (2000) (PubMed).
Synonyms and alternative names related to BRD2
Ring3 protein (CHLREDRAFT_190116), Ring3 protein (CHLREDRAFT_150233), Ring3 protein (CHLREDRAFT_182576), Ring3 protein (CHLREDRAFT_188250), bromodomain containing 2 (BRD2), bromodomain containing 2 (Brd2), bromodomain containing 2 S homeolog (brd2.S), bromodomain containing 2a (brd2a), AW228947, brd2, brd2-a, D6S113E, D17H6S113E, fe47f02, fi85h05, Frg-1, FSH, fsh, Fsrg-1, FSRG1, Fsrg1, fsrg1, mKIAA4005, NAT, Nat, nat, RING3, Ring3, ring3, RNF3, Rnf3, rnf3, wu:fe47f02, wu:fi85h05Protein level used designations for BRD2
- Ring3 protein
- O27.1.1
- bromodomain-containing 2
- bromodomain-containing protein 2
- female sterile homeotic-related gene 1
- really interesting new gene 3 protein
- collagen type XI alpha 2
- glutamate-cysteine ligase catalytic subunit
- ring finger protein 3
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