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- 抗原 See all NME1 蛋白
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-152
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NME1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ANCERTFIAI KPDGVQRGLV GEIIKRFEQK GFRLVGLKFM QASEDLLKEH YVDLKDRPFF AGLVKYMHSG PVVAMVWEGL NVVKTGRVML GETNPADSKP GTIRGDFCIQ VGRNIIHGSD SVESAEKEIG LWFHPEELVD YTSCAQNWIY E
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product NME1 蛋白
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Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) protein (GST tag)
NME1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 43-152) protein (GST tag)NME1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) protein (His tag)NME1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by reducing SDS-PAGE.
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 2-152) protein (His tag)Crystallography grade NME1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 2-152) protein (His tag)NME1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >98 % as determined by SDS-PAGE.
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (Transcript Variant 2) protein (His tag)NME1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
- 别名
- NDKA (NME1 产品)
- 别名
- AWD Protein, GAAD Protein, NB Protein, NBS Protein, NDKA Protein, NDPK-A Protein, NDPKA Protein, NM23 Protein, NM23-H1 Protein, AL024257 Protein, NM23-M1 Protein, NM23A Protein, NDPK-Z1 Protein, NM23-B Protein, NM23-Z1 Protein, ndpkz1 Protein, nm23b Protein, nme1 Protein, nme2 Protein, nme2b1 Protein, NME1 Protein, NME1-NME2 Protein, NM23-C1 Protein, ndpk-b Protein, ndpkb Protein, nm23-h2 Protein, nm23ndk Protein, puf Protein, NBR-A Protein, NBR-B Protein, NME1-1 Protein, nm23ndk-a Protein, NDK I Protein, NDPK I Protein, T30A10.80 Protein, T30A10_80 Protein, NDP kinase I Protein, NME/NM23 nucleoside diphosphate kinase 1 Protein, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 Protein, non-metastatic cells 1, protein (NM23A) expressed in Protein, NME/NM23 nucleoside diphosphate kinase 2 S homeolog Protein, NME/NM23 nucleoside diphosphate kinase 2 L homeolog Protein, nucleoside diphosphate kinase Protein, nucleoside diphosphate kinase 1 Protein, NME1 Protein, Nme1 Protein, nme2b.1 Protein, nme2.S Protein, nme2.L Protein, LOC547870 Protein, NDPK1 Protein, LOC107790563 Protein
- 背景
- Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 roves bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
- 分子量
- 44.4 kDa
- UniProt
- P15531
- 途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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