RPA2 Protein (AA 1-267, partial) (GST tag)
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- 抗原 See all RPA2 蛋白
- RPA2 (Replication Protein A2, 32kDa (RPA2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-267, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This RPA2 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MWNSGFESYG SSSYGGAGGY TQSPGGFGSP APSQAEKKSR ARAQHIVPCT ISQLLSATLV DEVFRIGNVE ISQVTIVGII RHAEKAPTNI VYKIDDMTAA PMDVRQWVDT DDTSSENTVV PPETYVKVAG HLRSFQNKKS LVAFKIMPLE DMNEFTTHIL EVINAHMVLS KANSQPSAGR APISNPGMSE AGNFGGNSFM PANGLTVAQN QVLNLIKACP RPEGLNFQDL KNQLKHMSVS SIKQAVDFLS NEGHIYSTVD DDHFKST
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product RPA2 蛋白
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Replication Protein A2, 32kDa (RPA2) (AA 81-217) protein (His-IF2DI Tag)
RPA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Replication Protein A2, 32kDa (RPA2) (AA 1-270) protein (His tag)RPA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Replication Protein A2, 32kDa (RPA2) (AA 1-270) protein (GST tag)RPA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Replication Protein A2, 32kDa (RPA2) (AA 1-267), (partial) protein (GST tag)RPA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Replication Protein A2, 32kDa (RPA2) protein (Myc-DYKDDDDK Tag)RPA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- RPA2 (Replication Protein A2, 32kDa (RPA2))
- 别名
- RFA2 (RPA2 产品)
- 别名
- REPA2 Protein, RPA32 Protein, 153194_at Protein, CG9273 Protein, Dmel\\CG9273 Protein, dRPA2 Protein, rpa Protein, zgc:109822 Protein, ik:tdsubc_2g1 Protein, xx:tdsubc_2g1 Protein, repa2 Protein, rpa32 Protein, RPA2 Protein, GB13976 Protein, LOC100230445 Protein, AA409079 Protein, AI325195 Protein, AU020965 Protein, RPA34 Protein, Rf-A2 Protein, replication protein A2 Protein, Replication protein A2 Protein, replication protein A2, 32kDa Protein, replication protein A 32 kDa subunit Protein, RPA2 Protein, Rpa2 Protein, rpa2 Protein, LOC725418 Protein, RPA2_2 Protein
- 背景
- As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Plays also a role in base excision repair (BER) probably through interaction with UNG. Through RFWD3 may activate CHEK1 and play a role in replication checkpoint control. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance
- 分子量
- 56.3 kDa
- UniProt
- P15927
- 途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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