TRAF6 Protein (AA 1-522, full length) (His-SUMO Tag)
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- 抗原 See all TRAF6 蛋白
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-522, full length
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TRAF6 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MSLLNCENSC GFSQSESDCC VAMASSCSAV TKDDSVGGTA STGNLSSSFM EEIQGYDVEF DPPLESKYEC PICLMALREA VQTPCGHRFC KACIIKSIRD AGHKCPVDNE ILLENQLFPD NFAKREILSL MVKCPNEGCL HKMELRHLED HQAHCEFALM DCPQCQRPFQ KFHINIHILK DCPRRQVSCD NCAASMAFED KEIHDQNCPL ANVICEYCNT ILIREQMPNH YDLDCPTAPI PCTFSTFGCH EKMQRNHLAR HLQENTQSHM RMLAQAVHSL SVIPDSGYIS EVRNFQETIH QLEGRLVRQD HQIRELTAKM ETQSMYVSEL KRTIRTLEDK VAEIEAQQCN GIYIWKIGNF GMHLKCQEEE KPVVIHSPGF YTGKPGYKLC MRLHLQLPTA QRCANYISLF VHTMQGEYDS HLPWPFQGTI RLTILDQSEA PVRQNHEEIM DAKPELLAFQ RPTIPRNPKG FGYVTFMHLE ALRQRTFIKD DTLLVRCEVS TRFDMGSLRR EGFQPRSTDA GV
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TRAF6 蛋白
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TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) protein (GST tag)
TRAF6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
TNF Receptor-Associated Factor 6 (TRAF6) (AA 413-522) protein (GST tag)TRAF6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) protein (Strep Tag)Crystallography grade TRAF6 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-530) protein (Strep Tag)Crystallography grade TRAF6 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
TNF Receptor-Associated Factor 6 (TRAF6) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TRAF6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 别名
- TRAF6 (TRAF6 产品)
- 别名
- MGC:3310 Protein, RNF85 Protein, 2310003F17Rik Protein, AI851288 Protein, C630032O20Rik Protein, rnf85 Protein, traf6 Protein, xtraf6 Protein, CG10961 Protein, DTRAF2 Protein, Dmel\\CG10961 Protein, TRAF Protein, TRAF2 Protein, TRAF6 Protein, Traf2 Protein, dTRAF2 Protein, dTRAF6 Protein, dTraf2 Protein, dtraf2 Protein, GB10539 Protein, fi15f02 Protein, wu:fi15f02 Protein, zgc:63704 Protein, TNF receptor associated factor 6 Protein, TNF receptor-associated factor 6 Protein, TNF receptor associated factor 6 L homeolog Protein, TNF-receptor-associated factor 6 Protein, TNF receptor associated factor 6 S homeolog Protein, TRAF6 Protein, Traf6 Protein, traf6.L Protein, traf6 Protein, LOC551819 Protein, traf6.S Protein
- 背景
- E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Ses to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that ses to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production
- 分子量
- 75.6 kDa
- UniProt
- Q9Y4K3
- 途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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