TWEAK Protein (AA 43-149) (His-SUMO Tag)
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- 抗原 See all TWEAK (TNFSF12) 蛋白
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- 蛋白类型
- Recombinant
- 产品特性
- AA 43-149
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TWEAK protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- SLGSRASLSA QEPAQEELVA EEDQDPSELN PQTEESQDPA PFLNRLVRPR RSAPKGRKTR ARRAIAAHYE VHPRPGQDGA QAGVDGTVSG WEEARINSSS PLRYNRQIGE FIVTRAGLYY LYCQVHFDEG KAVYLKLDLL VDGVLALRCL EEFSATAASS LGPQLRLCQV SGLLALRPGS SLRIRTLPWA HLKAAPFLTY FGLFQVH
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TNFSF12 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- 别名
- TNF12 (TNFSF12 产品)
- 别名
- APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
- 背景
- Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
- 分子量
- 38.85 kDa
- UniProt
- O43508
- 途径
- Apoptosis
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