TWEAK 蛋白
(Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TWEAK Protein (AA 99-330) (Fc Tag) | 人 | HEK-293 Cells |
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| TWEAK Protein (AA 43-249) (hFc Tag) | 人 | HEK-293 Cells |
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| TWEAK Protein (AA 106-249) (His-DYKDDDDK-Strep II Tag) | 人 | HEK-293T Cells |
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| TWEAK Protein (AA 1-134) (GST tag) | 人 | 小麦胚 |
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| TWEAK Protein (His tag) | 人 | Mammalian Cells |
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| TWEAK Protein (AA 1-249) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| TWEAK Protein (AA 1-249) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| TWEAK 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 46-249) (rFc Tag) | 小鼠 | HEK-293 Cells |
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| TWEAK Protein (AA 99-249) | 人 | CHO Cells |
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| TWEAK Protein (AA 1-249) | 人 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 93-249) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 105-249) (His tag) | 小鼠, 大鼠 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 94-249) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 94-249) (hFc Tag,His tag) | 小鼠 | Mammalian Cells |
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| TWEAK Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 53-249) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| TWEAK Protein (AA 148-247) (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- PI (Protein Interaction: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293T Cells
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠, 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >98 %
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >98 %
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 85 % as determined by SDS-PAGE.
Protein
- CC (Cell Culture: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 98 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Latest Publications for our TWEAK 蛋白
: "Fibroblast growth factor-inducible 14 (Fn14) is expressed in the lower genital tract and may play a role in amplifying inflammation during infection." in: Journal of reproductive immunology, Vol. 84, Issue 1, pp. 16-23, (2010) (PubMed).
Aliases for TWEAK 蛋白
TNF superfamily member 12 (TNFSF12) 蛋白tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12) 蛋白
tumor necrosis factor (ligand) superfamily, member 12 (Tnfsf12) 蛋白
TNF superfamily member 12 (Tnfsf12) 蛋白
APO3L 蛋白
Apo3l 蛋白
Dr3l 蛋白
DR3LG 蛋白
Dr3lg 蛋白
TWEAK 蛋白
Tweak 蛋白
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