TWEAK Protein (AA 99-249)
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- 抗原 See all TWEAK (TNFSF12) 蛋白
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 99-249
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宿主
- 人
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资源
- CHO Cells
- 产品特性
- ED50 < 1 ng/mL, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 43-249) protein (Fc Tag)
TNFSF12 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 106-249) protein (His-DYKDDDDK-Strep II Tag)TNFSF12 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 49-134) protein (GST tag)TNFSF12 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 1-134) protein (GST tag)TNFSF12 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Human TWEAK remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TWEAK should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- 别名
- TWEAK (TNFSF12 产品)
- 别名
- APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
- 背景
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TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-kappaB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
Synonyms: TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3-Ligand - 分子量
- 20-22 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q4ACW9
- 途径
- Apoptosis
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