Survivin Protein (AA 1-140, full length) (His-SUMO Tag)
-
- 抗原 See all Survivin (BIRC5) 蛋白
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-140
-
宿主
- 小鼠
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This Survivin protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGAPALPQIW QLYLKNYRIA TFKNWPFLED CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DNPIEEHRKH SPGCAFLTVK KQMEELTVSE FLKLDRQRAK NKIAKETNNK QKEFEETAKT TRQSIEQLAA
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product BIRC5 蛋白
-
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (Calmodulin (CaM))
BIRC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (GST tag)BIRC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-100) protein (GST tag)BIRC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (Strep Tag)Crystallography grade BIRC5 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140) protein (Strep Tag)Crystallography grade BIRC5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140), (full length) protein (His tag)BIRC5 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 别名
- BIRC5 (BIRC5 产品)
- 别名
- AP14 Protein, API4 Protein, EPR-1 Protein, AAC-11 Protein, Api4 Protein, TIAP Protein, survivin40 Protein, bir5a Protein, survivin Protein, BIR1 Protein, Su2 Protein, XBIR1 Protein, XSurvivin1 Protein, Xsvv1 Protein, api4 Protein, bir1-A Protein, epr-1 Protein, svv1 Protein, xSurvivin Protein, xsurv Protein, Su1 Protein, birc5.2 Protein, svv2 Protein, xSurvivin2 Protein, bir5b Protein, SIX Protein, birc5.2-a Protein, birc5.2-b Protein, baculoviral IAP repeat containing 5 Protein, baculoviral IAP repeat-containing 5 Protein, baculoviral IAP repeat containing 5a Protein, baculoviral IAP repeat-containing 5, gene 1 L homeolog Protein, baculoviral IAP repeat containing 5 L homeolog Protein, baculoviral IAP repeat containing 5b Protein, baculoviral IAP repeat containing 5 S homeolog Protein, BIRC5 Protein, Birc5 Protein, birc5a Protein, birc5.1.L Protein, birc5.2.L Protein, birc5b Protein, birc5.2.S Protein
- 背景
- Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex, directs CPC movent to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7 .
- 分子量
- 32.3 kDa
- UniProt
- O70201
- 途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
-
