Survivin 蛋白
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- 抗原 See all Survivin (BIRC5) 蛋白
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Survivin/BIRC5 Protein
- 序列
- Met 1-Asp142
- 产品特性
- Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BIRC5 蛋白
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Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (Calmodulin (CaM))
BIRC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (GST tag)BIRC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-100) protein (GST tag)BIRC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (Strep Tag)Crystallography grade BIRC5 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140) protein (Strep Tag)Crystallography grade BIRC5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140), (full length) protein (His tag)BIRC5 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140), (full length) protein (His-SUMO Tag)BIRC5 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, pH 7.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 别名
- Survivin/BIRC5 (BIRC5 产品)
- 别名
- AP14 Protein, API4 Protein, EPR-1 Protein, AAC-11 Protein, Api4 Protein, TIAP Protein, survivin40 Protein, bir5a Protein, survivin Protein, BIR1 Protein, Su2 Protein, XBIR1 Protein, XSurvivin1 Protein, Xsvv1 Protein, api4 Protein, bir1-A Protein, epr-1 Protein, svv1 Protein, xSurvivin Protein, xsurv Protein, Su1 Protein, birc5.2 Protein, svv2 Protein, xSurvivin2 Protein, bir5b Protein, SIX Protein, birc5.2-a Protein, birc5.2-b Protein, baculoviral IAP repeat containing 5 Protein, baculoviral IAP repeat-containing 5 Protein, baculoviral IAP repeat containing 5a Protein, baculoviral IAP repeat-containing 5, gene 1 L homeolog Protein, baculoviral IAP repeat containing 5 L homeolog Protein, baculoviral IAP repeat containing 5b Protein, baculoviral IAP repeat containing 5 S homeolog Protein, BIRC5 Protein, Birc5 Protein, birc5a Protein, birc5.1.L Protein, birc5.2.L Protein, birc5b Protein, birc5.2.S Protein
- 背景
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Background: Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
Synonym: Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4
- 分子量
- 20.4 kDa
- UniProt
- O15392
- 途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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