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Survivin 蛋白

This Recombinant Survivin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318193
发货至: 中国
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Quick Overview for Survivin 蛋白 (ABIN7318193)

抗原

See all Survivin (BIRC5) 蛋白
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

蛋白类型

Recombinant

宿主

  • 13
  • 5
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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Survivin/BIRC5 Protein

    序列

    Met 1-Asp142

    产品特性

    Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 7.5.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    Survivin/BIRC5

    背景

    API4,Apoptosis Inhibitor 4,Apoptosis Inhibitor Survivin,BIRC5,Baculoviral IAP Repeat-Containing Protein 5,IAP4,Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.

    分子量

    Calculated MW: 16.4 kDa

    Observed MW: 16-18 kDa

    基因ID

    332

    UniProt

    O15392

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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