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CD47 Protein (CD47) (partial) (AVI tag,His tag)

CD47 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN5608235
发货至: 中国
  • 抗原 See all CD47 蛋白
    CD47
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    partial
    宿主
    • 33
    • 14
    • 6
    • 6
    • 4
    • 2
    • 1
    资源
    • 41
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD47 protein is labelled with AVI tag,His tag.
    应用范围
    Western Blotting (WB), ELISA
    序列
    Gln 19 - Pro 139
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Endotoxin level is less than 1.0 EU per ug by the LAL method.
    Biological Activity Comment

    Measured by its binding ability in a functional ELISA. Immobilized Human SIRP alpha, Fc Tag at 2 μg/mL (100 uL/well) can bind Unconjugated Human CD47, His Tag, Avi Tag with a linear range of 2-12.8 ng/mL (QC tested).

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    Discover our top product CD47 蛋白
  • 应用备注
    This recombinant protein can be used for E, WB.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    10 mM Bicine, pH 8.3
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C,-80 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原
    CD47
    别名
    CD47 (CD47 产品)
    别名
    IAP Protein, MER6 Protein, OA3 Protein, 9130415E20Rik Protein, AA407862 Protein, AI848868 Protein, AW108519 Protein, B430305P08Rik Protein, Itgp Protein, CD47/IAP Protein, alkaline phosphatase, intestinal Protein, CD47 molecule Protein, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Protein, Cd47 molecule Protein, ALPI Protein, CD47 Protein, Cd47 Protein
    背景
    Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
    分子量
    16.9 kDa
    基因ID
    961
    NCBI登录号
    NP_942088
    UniProt
    Q08722
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