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CD47 Protein (CD47) (AA 19-140) (His tag)

CD47 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274237
发货至: 中国
  • 抗原 See all CD47 蛋白
    CD47
    蛋白类型
    Recombinant
    产品特性
    AA 19-140
    宿主
    • 38
    • 13
    • 6
    • 6
    • 4
    • 2
    • 1
    小鼠
    资源
    • 42
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD47 protein is labelled with His tag.
    原理
    Mouse CD47 Protein
    序列
    Gln19-Lys140
    产品特性
    Recombinant Mouse CD47 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln19-Lys140.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 1.33 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product CD47 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD47
    别名
    CD47 (CD47 产品)
    别名
    IAP Protein, MER6 Protein, OA3 Protein, 9130415E20Rik Protein, AA407862 Protein, AI848868 Protein, AW108519 Protein, B430305P08Rik Protein, Itgp Protein, CD47/IAP Protein, alkaline phosphatase, intestinal Protein, CD47 molecule Protein, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Protein, Cd47 molecule Protein, ALPI Protein, CD47 Protein, Cd47 Protein
    背景
    CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.
    分子量
    14.9 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.
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