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Glycoprotein / GP (Virus) (partial) protein (Fc Tag)

宿主: Human Herpesvirus 5 (HHV-5) 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. WB
产品编号 ABIN5608207
发货至: 中国
  • 抗原
    Glycoprotein / GP (Virus)
    蛋白类型
    Recombinant
    产品特性
    partial
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Herpesvirus 5 (HHV-5)
    资源
    • 9
    HEK-293 Cells
    标记
    Fc Tag
    应用范围
    Western Blotting (WB)
    序列
    Val 23 - Lys 700
    纯度
    >85 % as determined by SDS-PAGE.
    内毒素水平
    Endotoxin level is less than 1.0 EU per ug by the LAL method.
  • 应用备注
    This recombinant protein can be used for WB.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C,-80 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原
    Glycoprotein / GP (Virus)
    物质类
    Viral Protein
    背景
    Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. CMV Virus Envelope Glycoportein B (CMV-GB) can be cleaved into glycoprotein GP55. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. CMV-GB may be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Furthermore, CMV-GB can interact with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also, CMV-GB participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
    分子量
    104 kDa
    基因ID
    223014
    UniProt
    P13201
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