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JAG1 Protein (AA 1-1067, Extracellular Domain) (Fc Tag)

JAG1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
产品编号 ABIN5564384
发货至: 中国
  • 抗原 See all JAG1 蛋白
    JAG1 (Jagged 1 (JAG1))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-1067, Extracellular Domain
    宿主
    • 16
    • 4
    • 1
    小鼠
    资源
    • 7
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This JAG1 protein is labelled with Fc Tag.
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    小鼠
    产品特性
    Signal peptide and extracellular domain of mouse Jagged-1 (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG.
    纯度
    >90 % (SDS-PAGE)
    内毒素水平
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product JAG1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Inhibits adipogenesis of 3T3L-1 cells.

    限制
    仅限研究用
  • 状态
    Solid
    浓度
    Lot specific
    缓冲液
    Lyophilized. Contains PBS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    JAG1 (Jagged 1 (JAG1))
    别名
    Jagged-1 (JAG1 产品)
    别名
    AGS Protein, AHD Protein, AWS Protein, CD339 Protein, HJ1 Protein, JAGL1 Protein, ABE2 Protein, Gsfabe2 Protein, Htu Protein, Ozz Protein, Ser-1 Protein, JAG1 Protein, jag3 Protein, cb243 Protein, jag1 Protein, sb:cb243 Protein, serrateC Protein, jagged1 Protein, serrate Protein, serrate-1 Protein, x-serrate-1 Protein, jagged 1 Protein, jagged 1b Protein, jagged 1a Protein, jagged 1 L homeolog Protein, JAG1 Protein, Jag1 Protein, jag1 Protein, jag1b Protein, jag1a Protein, jag1.L Protein
    背景
    Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
    分子量
    ~150kDa (SDS-PAGE)
    UniProt
    Q9QXX0
    途径
    Notch Signaling, Stem Cell Maintenance
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