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JAG1 Protein (AA 34-1046) (His tag)

JAG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7454157
发货至: 中国
  • 抗原 See all JAG1 蛋白
    JAG1 (Jagged 1 (JAG1))
    蛋白类型
    Recombinant
    产品特性
    AA 34-1046
    宿主
    • 15
    • 5
    • 1
    资源
    • 7
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This JAG1 protein is labelled with His tag.
    原理
    Human Jagged 1/JAG1 Protein
    序列
    Gln34-Ser1046
    产品特性
    Recombinant Human Jagged 1/JAG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln34-Ser1046.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product JAG1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    JAG1 (Jagged 1 (JAG1))
    别名
    Jagged 1 (JAG1 产品)
    别名
    AGS Protein, AHD Protein, AWS Protein, CD339 Protein, HJ1 Protein, JAGL1 Protein, ABE2 Protein, Gsfabe2 Protein, Htu Protein, Ozz Protein, Ser-1 Protein, JAG1 Protein, jag3 Protein, cb243 Protein, jag1 Protein, sb:cb243 Protein, serrateC Protein, jagged1 Protein, serrate Protein, serrate-1 Protein, x-serrate-1 Protein, jagged 1 Protein, jagged 1b Protein, jagged 1a Protein, jagged 1 L homeolog Protein, JAG1 Protein, Jag1 Protein, jag1 Protein, jag1b Protein, jag1a Protein, jag1.L Protein
    背景
    JAGGED1 (JAG1) is composed of a relatively small intracellular domain, a transmembrane domain and a larger extracellular component. JAG1 is widely expressed throughout mammalian development, across many tissues and developmental stages. The Notch signaling pathway and JAG1 in particular have been implicated in multiple forms of cancer and multiple aspects of cancer biology including tumor angiogenesis, neoplastic cell growth, cancer stem cell maintenance and the metastatic process.
    分子量
    111.56 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.
    途径
    Notch Signaling, Stem Cell Maintenance
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