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IL4 Receptor Protein (AA 26-232) (His tag,AVI tag,Biotin)

IL4R 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
产品编号 ABIN4949032
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 蛋白
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 26-232
    宿主
    • 22
    • 11
    • 7
    • 5
    • 4
    • 1
    资源
    • 22
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This IL4 Receptor protein is labelled with His tag,AVI tag,Biotin.
    应用范围
    Functional Studies (Func)
    品牌
    MABSol®,PrecisionAvi
    序列
    AA 26-232
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 26.9 kDa. The protein migrates as 40-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL4R 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL-4 R alpha (IL4R 产品)
    别名
    IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
    背景
    IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
    分子量
    26.9 kDa
    NCBI登录号
    NP_000409
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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