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DLL1 Protein (AA 18-540) (His tag)

DLL1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2870633
发货至: 中国
  • 抗原 See all DLL1 蛋白
    DLL1 (delta-Like 1 (DLL1))
    蛋白类型
    Recombinant
    产品特性
    AA 18-540
    宿主
    • 15
    • 7
    • 2
    资源
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DLL1 protein is labelled with His tag.
    序列
    AA 18-540
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product DLL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 150 mM NaCl, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    DLL1 (delta-Like 1 (DLL1))
    别名
    DLL1 (DLL1 产品)
    别名
    X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
    背景
    Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
    分子量
    58.4 kDa
    NCBI登录号
    NP_005609
    途径
    Notch Signaling, Stem Cell Maintenance
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