DLL1 Protein (AA 18-540) (His tag)
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- 抗原 See all DLL1 蛋白
- DLL1 (delta-Like 1 (DLL1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 18-540
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DLL1 protein is labelled with His tag.
- 原理
- Human DLL1/Delta1 Protein
- 序列
- Gln18-Gly540
- 产品特性
- Recombinant Human DLL1/Delta1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln18-Gly540.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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delta-Like 1 (DLL1) protein (Fc Tag)
DLL1 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (AA 18-109) protein (GST tag)DLL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
delta-Like 1 (DLL1) (AA 1-545), (Extracellular Domain) (Active) protein (Fc Tag)DLL1 宿主: 人 宿主: CHO Cells Recombinant >90 % (SDS-PAGE) SDS Active
delta-Like 1 (DLL1) (AA 569-722) protein (His tag)Crystallography grade DLL1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 (DLL1) (AA 569-723) protein (His tag)Crystallography grade DLL1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 (DLL1) (AA 18-545) protein (His tag)Crystallography grade DLL1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 (DLL1) (AA 18-545) protein (His tag)Crystallography grade DLL1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 (DLL1) (AA 18-535) protein (rho-1D4 tag)Crystallography grade DLL1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
delta-Like 1 (DLL1) (AA 536-722) protein (rho-1D4 tag)Crystallography grade DLL1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in 50 mM Tris, 150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DLL1 (delta-Like 1 (DLL1))
- 别名
- DLL1 (DLL1 产品)
- 别名
- X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
- 背景
- DLL1, a Notch signaling ligand, is significantly overexpressed in ERα luminal breast cancer. Intriguingly, DLL1 overexpression correlates with poor prognosis in ERα luminal breast cancer, but not in other subtypes of breast cancer. In addition, this effect is specific to DLL1, as other Notch ligands (DLL3, JAGGED1, and JAGGED2) do not influence the clinical outcome of ERα patients. DLL1-mediated Notch signaling in breast cancer is important for tumor cell proliferation, angiogenesis, and cancer stem cell function.
- 分子量
- 57.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- NCBI登录号
- NP_005609
- 途径
- Notch Signaling, Stem Cell Maintenance
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