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RANKL Protein (AA 152-317, Soluble) (DYKDDDDK Tag)
TNFSF11
宿主: 人, 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
SDS
产品细节
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抗原
See all RANKL (TNFSF11) 蛋白
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
蛋白类型
Recombinant
产品特性
Soluble, AA 152-317
宿主
All origins for RANKL 蛋白
人, 小鼠
资源
All sources for RANKL 蛋白
HEK-293 Cells
标记
This RANKL protein is labelled with DYKDDDDK Tag.
应用范围
SDS-PAGE (SDS)
特异性
Binds to human and mouse RANK.
交叉反应
人, 小鼠
产品特性
Human RANKL (aa 152-317) is fused at the N-terminus to a FLAG®-tag.
纯度
>95 % (SDS-PAGE)
内毒素水平
<0.01EU/μg purified protein (LAL test, Lonza).
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Lyophilized
溶解方式
Reconstitute with 100 μL sterile water.
浓度
Lot specific
缓冲液
Lyophilized. Contains PBS.
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
有效期
6 months
目标详细情况
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抗原
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
别名
RANKL (TNFSF11 产品 )
别名
CD254 Protein, ODF Protein, OPGL Protein, OPTB2 Protein, RANKL Protein, TRANCE Protein, hRANKL2 Protein, sOdf Protein, TNFSF11 Protein, Ly109l Protein, OPG Protein, Trance Protein, cd254 Protein, odf Protein, opgl Protein, optb2 Protein, rankl Protein, sodf Protein, tnfsf11 Protein, trance Protein, TNF superfamily member 11 Protein, tumor necrosis factor (ligand) superfamily, member 11 Protein, TNF receptor superfamily member 11b Protein, TNF superfamily member 11 L homeolog Protein, TNFSF11 Protein, Tnfsf11 Protein, TNFRSF11B Protein, tnfsf11.L Protein
背景
RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of breast cancer.
分子量
~28kDa (SDS-PAGE)
UniProt
O14788
途径
NF-kappaB Signaling
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