SMAD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all SMAD2 蛋白
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SMAD2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human SMAD2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SMAD2 蛋白
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SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) protein (GST tag)
SMAD2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)SMAD2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 1-467) protein (His tag)SMAD2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
SMAD, Mothers Against DPP Homolog 2 (SMAD2) protein (GST tag,His tag)SMAD2 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)Crystallography grade SMAD2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) protein (His tag)Crystallography grade SMAD2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
SMAD, Mothers Against DPP Homolog 2 (SMAD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SMAD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- 别名
- Smad2 (SMAD2 产品)
- 别名
- JV18 Protein, JV18-1 Protein, MADH2 Protein, MADR2 Protein, hMAD-2 Protein, hSMAD2 Protein, jv18 Protein, Xmad2 Protein, madh2 Protein, madr2 Protein, XSmad2 Protein, hmad-2 Protein, hsmad2 Protein, jv18-1 Protein, smad-2 Protein, fj43c06 Protein, wu:fj43c06 Protein, 7120426M23Rik Protein, Madh2 Protein, Madr2 Protein, Smad-2 Protein, mMad2 Protein, MAD homolog 2 Protein, Mothers against DPP homolog 2 Protein, SMAD 2 Protein, Smad2 Protein, SMAD family member 2 Protein, SMAD family member 2-Z Protein, SMAD family member 2 S homeolog Protein, SMAD2 Protein, SMAD2Z Protein, smad2 Protein, smad2.S Protein, Smad2 Protein
- 背景
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.
- 分子量
- 52.1 kDa
- NCBI登录号
- NP_001003652
- 途径
- Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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