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RRM2B Protein (Myc-DYKDDDDK Tag)

RRM2B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731210
发货至: 中国
  • 抗原 See all RRM2B 蛋白
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
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    • 1
    HEK-293 Cells
    标记
    This RRM2B protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human RRM2B / P53R2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RRM2B 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    别名
    Rrm2b,p53r2 (RRM2B 产品)
    别名
    p53r2 Protein, RRM2B Protein, MTDPS8A Protein, MTDPS8B Protein, P53R2 Protein, p53R2 Protein, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Protein, ribonucleotide reductase regulatory TP53 inducible subunit M2B Protein, ribonucleotide reductase M2 B (TP53 inducible) Protein, rrm2b.S Protein, RRM2B Protein, rrm2b Protein, Rrm2b Protein
    背景
    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
    分子量
    40.6 kDa
    NCBI登录号
    NP_056528
    途径
    p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
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