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ROR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ROR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731082
发货至: 中国
  • 抗原 See all ROR1 蛋白
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 33
    • 8
    • 8
    • 8
    • 3
    • 1
    • 1
    资源
    • 26
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This ROR1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ROR1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ROR1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Hojjat-Farsangi, Jeddi-Tehrani, Daneshmanesh, Mozaffari, Moshfegh, Hansson, Razavi, Sharifian, Rabbani, Österborg, Mellstedt, Shokri: "Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).

  • 抗原
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    别名
    Ror1 (ROR1 产品)
    别名
    NTRKR1 Protein, dJ537F10.1 Protein, 2810404D04Rik Protein, Ntrkr1 Protein, mRor1 Protein, RGD1559469 Protein, ROR1 Protein, fi34e02 Protein, si:dkey-209n16.1 Protein, wu:fi34e02 Protein, receptor tyrosine kinase like orphan receptor 1 Protein, receptor tyrosine kinase-like orphan receptor 1 Protein, ROR1 Protein, Ror1 Protein, ror1 Protein
    背景
    This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    104.1 kDa
    NCBI登录号
    NP_005003
    途径
    RTK signaling, WNT signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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