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Epiregulin Protein (EREG)

EREG 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
产品编号 ABIN2729684
发货至: 中国
  • 抗原 See all Epiregulin (EREG) 蛋白
    Epiregulin (EREG)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 4
    • 1
    资源
    • 7
    • 4
    • 2
    • 2
    大肠杆菌(E. Coli)
    应用范围
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human Proepiregulin protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5units/mg.
    Top Product
    Discover our top product EREG 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    注意事项
    Resuspend the protein in the desired concentration in proper buffer
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    Epiregulin (EREG)
    别名
    Proepiregulin (EREG 产品)
    别名
    EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
    背景
    This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
    分子量
    5.6 kDa
    NCBI登录号
    NP_001423
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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