Epiregulin Protein (EREG) (AA 63-108) (Fc Tag)
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- 抗原 See all Epiregulin (EREG) 蛋白
- Epiregulin (EREG)
- 蛋白类型
- Recombinant
- 产品特性
- AA 63-108
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Epiregulin protein is labelled with Fc Tag.
- 原理
- Human EREG Protein
- 序列
- Val63-Leu108
- 产品特性
- Recombinant Human EREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val63-Leu108.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EREG 蛋白
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Epiregulin (EREG) (AA 56-101) protein (Fc Tag)
EREG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epiregulin (EREG) (AA 60-108) protein (His-IF2DI Tag)EREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Epiregulin (EREG) (AA 1-169) protein (GST tag)EREG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Epiregulin (EREG) (AA 32-117) protein (GST tag)EREG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Epiregulin (EREG) (AA 30-169) protein (rho-1D4 tag)Crystallography grade EREG 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 63-108) protein (rho-1D4 tag)Crystallography grade EREG 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 56-101) protein (rho-1D4 tag)Crystallography grade EREG 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Epiregulin (EREG) (AA 23-162) protein (rho-1D4 tag)Crystallography grade EREG 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Epiregulin (EREG)
- 别名
- EREG (EREG 产品)
- 别名
- EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
- 背景
- Epidermal growth factor receptor (EGFR) regulates many crucial cellular programs, with seven different activating ligands shaping cell signaling in distinct ways.EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. As a consequence, EREG or EPGN induce less stable EGFR dimers than EGF-making them partial agonists of EGFR dimerization. Unexpectedly, this weakened dimerization elicits more sustained EGFR signaling than seen with EGF, provoking responses in breast cancer cells associated with differentiation rather than proliferation.
- 分子量
- 32.6 kDa. Due to glycosylation, the protein migrates to 37-42 kDa based on Tris-Bis PAGE result.
- UniProt
- O14944
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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