PRKAR2B Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PRKAR2B 蛋白
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PRKAR2B protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PRKAR2B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAR2B 蛋白
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Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 304-413) protein (GST tag)
PRKAR2B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 1-416) protein (Strep Tag)Crystallography grade PRKAR2B 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 2-418) protein (His tag)Crystallography grade PRKAR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
- 别名
- Prkar2b (PRKAR2B 产品)
- 别名
- MGC83177 Protein, PRKAR2B Protein, AI451071 Protein, AW061005 Protein, PKARIIbeta Protein, Pkarb2 Protein, RII(beta) Protein, RATDNA Protein, PRKAR2 Protein, RII-BETA Protein, protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog Protein, protein kinase cAMP-dependent type II regulatory subunit beta Protein, protein kinase, cAMP-dependent, regulatory, type II, beta Protein, protein kinase, cAMP dependent regulatory, type II beta Protein, protein kinase cAMP-dependent type 2 regulatory subunit beta Protein, prkar2b.S Protein, PRKAR2B Protein, prkar2b Protein, Prkar2b Protein
- 背景
- CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol.
- 分子量
- 46.1 kDa
- NCBI登录号
- NP_002727
- 途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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