GCH1 Protein (His tag)
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- 抗原 See all GCH1 蛋白
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GCH1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human GTP cyclohydrolase 1 (GCH1) (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GCH1 蛋白
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GTP Cyclohydrolase 1 (GCH1) (AA 1-250) protein (GST tag)
GCH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
GTP Cyclohydrolase 1 (GCH1) (AA 84-172) protein (GST tag)GCH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
GTP Cyclohydrolase 1 (GCH1) (AA 1-250) protein (Strep Tag)Crystallography grade GCH1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
GTP Cyclohydrolase 1 (GCH1) (AA 12-241) protein (His tag)Crystallography grade GCH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- Abstract
- GCH1 产品
- 别名
- DYT14 Protein, DYT5 Protein, DYT5a Protein, GCH Protein, GTP-CH-1 Protein, GTPCH1 Protein, HPABH4B Protein, GTP-CH Protein, GTPCH Protein, Gch Protein, MGC89622 Protein, gch1a Protein, wu:fc16b10 Protein, zgc:195269 Protein, GTP cyclohydrolase 1 Protein, GTP cyclohydrolase 1-like Protein, GCH1 Protein, Gch1 Protein, gch1 Protein, Weevi_1190 Protein, Halhy_0838 Protein, Sinme_1220 Protein, Sphch_1077 Protein, LOC100136794 Protein
- 背景
- This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described however, not all variants give rise to a functional enzyme.
- 分子量
- 27.7 kDa
- NCBI登录号
- NP_001019195
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