FEN1 Protein (Myc-DYKDDDDK Tag)
FEN1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
-
- 抗原 See all FEN1 蛋白
- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This FEN1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human FEN1 / RAD2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FEN1 蛋白
-
Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-110) protein (GST tag)
FEN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) protein (GST tag)FEN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
- 别名
- Fen1,rad2 (FEN1 产品)
- 别名
- FEN-1 Protein, FEN1 Protein, AW538437 Protein, MF1 Protein, RAD2 Protein, cb879 Protein, fen-1 Protein, fen1 Protein, mf1 Protein, rad2 Protein, xFEN1a Protein, flap structure-specific endonuclease 1 Protein, flap endonuclease 1-like Protein, Flap endonuclease-1 Protein, 5'-3' exonuclease family protein Protein, flap structure specific endonuclease 1 Protein, flap structure-specific endonuclease 1 L homeolog Protein, nuclease, Rad2 family Protein, FEN1 Protein, LOC100808044 Protein, Bm1_49605 Protein, AT5G26680 Protein, Fen1 Protein, fen1 Protein, fen1.L Protein
- 背景
- The protein encoded by this gene removes 5&apos overhanging flaps in DNA repair and processes the 5&apos ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5&apos end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
- 分子量
- 42.4 kDa
- NCBI登录号
- NP_004102
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
-
You are here:
