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ATF2 Protein (His tag)

ATF2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715020
发货至: 中国
  • 抗原 See all ATF2 蛋白
    ATF2 (Activating Transcription Factor 2 (ATF2))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 1
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    • 1
    资源
    • 3
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    大肠杆菌(E. Coli)
    标记
    This ATF2 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ATF2 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATF2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    ATF2 (Activating Transcription Factor 2 (ATF2))
    别名
    Atf2 (ATF2 产品)
    别名
    CRE-BP1 Protein, CREB2 Protein, HB16 Protein, TREB7 Protein, CG12850 Protein, CG3749 Protein, dATF-2 Protein, DmelCG30420 Protein, CG30420 Protein, CHN1 Protein, Atf-2 Protein, CRE-BP Protein, Creb2 Protein, D130078H02Rik Protein, D18875 Protein, Tg(Gzma-Klra1)7Wum Protein, mXBP Protein, atf2-A Protein, atf2l Protein, activating transcription factor 2 Protein, Activating transcription factor-2 Protein, activating transcription factor 2 S homeolog Protein, ATF2 Protein, Atf-2 Protein, Atf2 Protein, atf2.S Protein, atf2 Protein
    背景
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
    分子量
    54.4 kDa
    NCBI登录号
    NP_001871
    途径
    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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