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ANTXR1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ANTXR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714756
发货至: 中国
  • 抗原 See all ANTXR1 蛋白
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 11
    • 3
    • 1
    资源
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This ANTXR1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Anthrax toxin receptor 1 / ANTXR1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ANTXR1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    别名
    Anthrax Toxin Receptor 1 (ANTXR1 产品)
    别名
    ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein
    背景
    This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
    分子量
    38.3 kDa
    NCBI登录号
    NP_444262
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