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ANTXR1 Protein (His tag)

ANTXR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092772
发货至: 中国
  • 抗原 See all ANTXR1 蛋白
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 3
    • 1
    资源
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This ANTXR1 protein is labelled with His tag.
    原理
    Recombinant human ANTXR1 protein with C-terminal 6xHis tag
    特异性
    ANTXR1 (Glu33-Ser321) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product ANTXR1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    别名
    ANTXR1 (ANTXR1 产品)
    别名
    ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein
    背景
    Synonymes: ATR
    Description: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
    分子量
    predicted molecular mass of 33.2 kDa after removal of the signal peptide. The apparent molecular mass of ANTXR1-His is 35-55 kDa due to glycosylation.
    UniProt
    Q9H6X2
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