ANTXR1 Protein (His tag)
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- 抗原 See all ANTXR1 蛋白
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ANTXR1 protein is labelled with His tag.
- 原理
- Recombinant human ANTXR1 protein with C-terminal 6xHis tag
- 特异性
- ANTXR1 (Glu33-Ser321) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ANTXR1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 别名
- ANTXR1 (ANTXR1 产品)
- 别名
- ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein
- 背景
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Synonymes: ATR
Description: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008] - 分子量
- predicted molecular mass of 33.2 kDa after removal of the signal peptide. The apparent molecular mass of ANTXR1-His is 35-55 kDa due to glycosylation.
- UniProt
- Q9H6X2
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