ANTXR1 Protein (Fc Tag)
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- 抗原 See all ANTXR1 蛋白
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ANTXR1 protein is labelled with Fc Tag.
- 原理
- Recombinant Human TEM8/ATR Protein (Fc Tag)
- 序列
- Met 1-Ser321
- 产品特性
- A DNA sequence encoding the human ANTXR1 (Q9H6X2-4) (Met1-Ser321) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product ANTXR1 蛋白
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anthrax Toxin Receptor 1 (ANTXR1) (AA 95-204) protein (His-IF2DI Tag)
ANTXR1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
anthrax Toxin Receptor 1 (ANTXR1) (AA 1-368) protein (GST tag)ANTXR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
anthrax Toxin Receptor 1 (ANTXR1) (AA 201-305) protein (GST tag)ANTXR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 别名
- TEM8/ATR (ANTXR1 产品)
- 别名
- ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein
- 背景
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Background: ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR, MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key proteins. ANTXR1 interacts with extracellular matrix proteins and with the actin cytoskeleton. It functions in cell attachment and migration. ANTXR1 also mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
Synonym: Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ANTXR1, ATR, TEM8
- 分子量
- 59.4 kDa
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